The UK has recorded 44,104 new COVID-19 cases and 73 more coronavirus-related deaths in the latest 24-hour period, according to government data.
The figures compare with 46,558 new cases and 96 deaths announced on Tuesday, and 42,302 cases and 49 deaths which were recorded this time last week.
Since the pandemic began, a total of 128,896 people in the UK have died within 28 days of testing positive for COVID-19.
Separate figures published by the Office for National Statistics (ONS) show there have been 154,000 deaths registered in the UK where COVID-19 was mentioned on the death certificate.
Some 39,035 people had their first jab on Tuesday, meaning that 46,388,744 have now received at least one COVID vaccination shot in the UK.
Another 161,279 people had their second shot yesterday, so 36,404,566 people are now fully inoculated.
It comes as Boris Johnson apologised to businesses impacted by a rising number of workers having to self-isolate due to coming into close contact with a positive coronavirus case.
Speaking at the last PMQs before the summer recess, the prime minister – himself isolating at Chequers after coming into contact with COVID-positive Health Secretary Sajid Javid last week – said “everybody understands the inconvenience of being pinged”.
Labour leader Sir Keir Starmer also pressed the prime minister on whether someone who is pinged by the NHS COVID-19 app should isolate following mixed messages from government ministers.
“When it comes to creating confusion, the prime minister is a super-spreader,” Sir Keir noted.
Immediately after PMQs, Sir Keir was himself told to isolate after one of his children tested positive. It is the fourth time the Labour leader has had to quarantine.
Meanwhile, around nine in 10 adults in all parts of the UK are now likely to have COVID-19 antibodies.
According to the figures from the ONS, the estimates range from 88.6% in Scotland to 92.6% in Wales, with 90.0% for Northern Ireland and 91.9% for England.
The presence of coronavirus antibodies suggests someone has had the infection in the past or has been vaccinated.